GREENSENSOR: Non-invasive lactate sensors enhanced via Iron Oxide nanoparticles coming from the valorization of a steel by-product.
Project team:
GREENSENSOR project Titled: “Non-invasive lactate sensors enhanced via Iron Oxide nanoparticles coming from the valorization of a steel by-product” is a project funded by Ministerio de Ciencia e Innovación in 2022.
This is a project Coordinated by CELSA INNOVATION GROUP in collaboration with Microtech Lab, from CAT MECH TENIO group of UPC-BarcelonaTech and Ona Labs InnoHub.
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GREENSENSOR will create a novel intelligent wearable for monitoring lactate using sweat instead of blood. The project proposes to create a wearable that takes advantage of a novel microfluidic system that ensures the efficient capture of sweat and the continuous circulation of new samples, which embeds a lactate chronoamperometric sensor enhanced using magnetic nanoparticles, coming from a revalorization route of a steel manufacturing by-product.
The main benefit is that the magnetic behavior of the obtained nanoparticles together with its beneficial surface-to-volume ratio enhances the range of current electrochemical sensors. Figure 1 shows a transmission electron microscope picture of the obtained nanoparticle, without and with functionalization. This enhanced range enables applications in the field of athlete training that before were only available in clinical labs.
Figure 1 shows a transmission electron microscope picture of the obtained nanoparticle, without and with functionalization.
The objectives of the MICROTECH LAB subproject within GREENSENSOR are the design, development, integration, and validation of microfluidics with the embedded electrochemical system functionalized with revalorized nanoparticles. Figure 2 shows the setup developed in the lab to test electrochemically different analytes. This novel proposed strategy will increase the accuracy of these devices even though they are portable and handheld. Therefore, these will enable the possibility to use these devices near the need: either at home or public places with acceptable accuracies.
Figure 2 setup developed in the lab to test electrochemically different analytes.
The consortium vision is that GREENSESOR contributes to a paradigm shift in PRECISION MEDICINE near the PATIENT and the REVALORIZATION of by-products such as the use of MILL SCALE from a waste to a high-added value product. The research experience by the consortium represents an optimum blending of the interdisciplinary knowledge needed to develop successful projects in the area of nanomaterials.
Kick-off meeting in Terrassa 3rd of February 2023.
Acknowledgment
This project is partially supported through the call for RETOS COLABORACIÓN from by Ministerio de Ciencia e Innovación ref. nº CPP2021-009021
Publications:
G. Rabost-Garcia, V. Colmena, J.Aguilar-Torán, J.Vieyra Galí, J. Punter-Villagrasa, J.Casals-Terré et al. (2023) Non-Invasive Multiparametric Approach To Determine Sweat–Blood Lactate Bioequivalence. ACS Sensors DOI: 10.1021/acssensors.2c02614